ARAVA is indicated in adults for the treatment of active rheumatoid arthritis (RA):
To reduce signs
to hinder structural damage as evidenced by X-ray erosions and joint space narrowing
to improve bodily function
Take this medication only as instructed by your physician. Do not take more of it, do not take it more frequently, and don't take it for an extended period than your doctor ordered.
The dosage of this medication will be different for different individuals. Follow your physician's orders or the instructions on the tag. This information contains only the average dosages of the medicine. If your dose differs, do not change it unless your doctor informs you to accomplish that.
The amount of medication that you take depends on the power of the medicine. In Addition, the amount of doses you take each day, the time allowed between doses, and the duration of time you take the medicine depend on the medical problem that you are utilizing the medicine.
For oral dosage form (tablets):
For rheumatoid arthritis:
AdultsAt first, 100 milligrams (mg) one time a day for three days, then-20 mg once a day. Your own doctor may adjust the dosage as required.
ChildrenUse and dose must certanly be decided by your physician.
In the event you skip a dose of this medicine, take it as soon as you can. However when it is nearly time for your following dose, skip the missed dose and return to your usual dosing timetable. Do not double doses.
It's very essential that your physician monitor your progress at regular visits to make sure that this medication is working properly. Blood tests may be needed to check for unwanted side effects.
Using this medicine while you're pregnant can hurt your unborn child. Use an effective form of birth control to keep from getting pregnant. In case you believe you've become pregnant while utilizing the medication, tell your doctor right away.
If the dad is using it when his sexual partner becomes pregnant leflunomide may also lead to birth defects. Guys taking leflunomide ought to use condoms as a kind of birth control during intercourse. A guy intending to father a child should stop using this medicine and check with his doctor immediately.
Severe skin reactions can happen with this medication. Stop using this medication and always check with your doctor right away if you have any one of the following signs while taking this medication: blistering, peeling, or loosening of skin; chills; itching; joint or muscle pain; reddish skin lesions, typically with a purple center; sores, ulcers, or white spots inside the mouth or in the lips; or unusual tiredness or weakness.
Liver problems may occur throughout the time you are using this medicine. Stop using this medicine and talk with your physician straight away in case you're having over one of the symptoms: abdominal or stomach soreness or tenderness; clay-colored stools; dark urine; reduced appetite; temperature; headaches; lack of appetite; nausea or vomiting; skin rash; swelling of the toes or lower legs; unusual tiredness or weakness; or yellow eyes or skin.
Leflunomide can temporarily reduce the amount of white blood cells in your blood, raising the odds of acquiring disease. Additionally it may diminish the amount of platelets, that are necessary for proper blood-clotting. When that happens, there are specific precautions you may take, particularly when your blood count is reduced, to lessen the danger of infection or bleeding:
If you're able to, avoid individuals with attacks. Check with your doctor immediately in case you believe you're getting disease or if you get a fever or chills, coughing or hoarseness, lower-back or side pain, or painful or difficult urination
Check with your own physician promptly if you notice any unusual bleeding or bruising; black, tarry stools; blood in the urine or stools; or pinpoint red spots on your own skin.
Be careful when working with a regular toothbrush, dental floss, or toothpick. Your medical doctor, dentist, or nurse might recommend other ways to clean your own teeth and gums. Check to your own medical doctor before having any dental work completed.
Do not touch your eyes or the inside of your own nose unless you have simply cleaned your hands and haven't handled anything else in the interim,.
Be careful not to cut yourself whenever you're using sharp objects for example a safety razor or fingernail or toenail cutters.
Avoid contact sports or other circumstances where bruising or harm can happen.
Check with your doctor right away if you got a cough with or without a temperature, shortness of breath, or any difficulty with respiration.
You'll need to have a skin test for tuberculosis before you start using this medicine. Tell your doctor if you or anyone in your house has ever had a favorable reaction to a tuberculosis test.
Applying this medicine may increase your risk of having severe infections or cancer. Speak to your doctor if you have issues relating to this danger.
Do not take other medications unless they have been discussed with your physician. This consists of prescription or non-prescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
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