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Nexium relieves heartburn and other signs resulting from the back-flow of stomach acid into the duct towards the stomach (the esophagus)a condition known as gastroesophageal reflux disease. It is also suggested to fix the damage (erosive esophagitis) that reflux disease can cause. Approved in combination with the antibiotics amoxicillin and clarithromycin, Nexium is also used to treat the illness that causes most duodenal ulcers (ulcers occurring just beyond the exit from the belly). Nexium works by lowering the generation of stomach acid. Use Nexium as instructed by your doctor. Take Nexium a minimum of one hour before meals. Be careful to swallow it whole. When you have difficulty swallowing capsules, you can open the capsule and cautiously pour the pellets onto one tbsp of applesauce. The applesauce really should not be hot. Blend within the pellets, then consume the applesauce immediately, without eating. In the event you skip a dose of Nexium, take it when you remember. If it's nearly time for your next dose, skip the one you missed and return to your regular schedule. Never take more than one dose at the same time. Ask your physician any questions that may have concerning the best way to use Nexium. Don't use Nexium if: You're sensitive to any ingredient in Nexium or to similar medicines (eg, omeprazole) you are taking certain HIV protease inhibitors (eg, atazanavir, nelfinavir). Contact your doctor immediately if one of these apply to you. Some medical conditions may interact with Nexium. Tell your doctor if you got any health conditions, particularly if any of these apply to you: if you are pregnant, intending to become pregnant, or are breastfeeding If you're using any prescription or non-prescription medicine, herbal preparation, or dietary supplement if you have allergies to medicines, foods, or other materials if you have liver problems or gut or bowel cancer. Some medications may interact with Nexium. Inform your doctor should you be using any other medications, particularly the following: Voriconazole as it may increase the danger of Nexium's side effects Anticoagulants (eg, warfarin), cilostazol, digoxin, or saquinavir because the danger of these side effects might be increased by Nexium. Azole antifungals (eg, nizoral), clopidogrel, HIV protease inhibitors (eg, atazanavir, nelfinavir), or iron because their usefulness may be reduced by Nexium. This might not be a whole list of all relationships that may occur. Ask your health care provider if Nexium might interact with other medicines which you take. Check with your physician before you start, stop, or adjust the dose of any medication. Important security tips: Nexium can cause dizziness. This effect could be worse for it with alcohol or particular medications. Use Nexium with caution. Don't drive or execute other possible unsafe tasks until you know how you respond to it. Contact your doctor if you have any symptoms of a bleeding ulcer, like black, tarry stools or vomit that looks like coffee grounds, or if you experience throat pain, chest pain, acute belly malady, or difficulty swallowing. Nexium may interfere with specific laboratory tests. Be sure your doctor and lab staff know you are using Nexium. Nexium must be utilized with extreme care in children; safety and effectiveness in children have not been affirmed. Maternity and breast feeding: If you become pregnant, contact your doctor. You're going to have to discuss the hazards and advantages of using Nexium while you're pregnant. It is not known if Nexium is present in breast milk. Do not breast-feed while using Nexium. 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