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Reglan is used for short term treatment of gastro-esophageal reflux disease (GERD) in certain patients who don't respond to other therapy. It is used as a treatment for symptoms of a specific digestive problem in diabetic patients (diabetic gastroparesis). Reglan is a gastro-intestinal stimulant and antinauseant. It works by raising the movements of the abdomen and bowels to help transfer food and acid out of the stomach more swiftly. It also works in certain areas within the brain to decrease nausea. Use Reglan as directed by your doctor. Unless directed otherwise by your doctor take Reglan by mouth 30-minutes before meals. It may take several days to weeks for Reglan to work. Don't stop taking Reglan without consulting your physician. In the event that you miss a dose of Reglan, take it as soon as possible. If it is nearly time for your following dose, skip the missed dose and go back to your regular dosing schedule. Don't take more than one dose at once. Ask your doctor any questions that might have concerning how exactly to use Reglan. Do NOT use Reglan if: You're sensitive to any ingredient in Reglan you have seizures (eg, epilepsy); bleeding, blockage, or perforation in your abdomen or intestines; or tumors on your own adrenal gland (pheochromocytoma) You're using cabergoline or pergolide You're using medications, such as phenothiazines (eg, chlorpromazine), that may cause extrapyramidal reactions (strange, involuntary muscle actions of the head, neck, or limbs). Check with your own physician in case you are unsure if any of your medications may cause extrapyramidal reactions. Contact your physician right away if these apply to you. Some health conditions may interact with Reglan. Tell your physician or pharmacist if you have any medical conditions, especially if any of the following apply to you: If you're pregnant, planning to become pregnant, or are breast feeding If you're using any prescription or non-prescription medicine, herbal preparation, or dietary supplement In case you are allergic to medications, foods, or other substances When you have a history of mental or mood problems (eg, depression) or suicidal thoughts or actions if you have a history of asthma, heart failure, hypertension, diabetes, Parkinson disease, blood problems (eg, porphyria), kidney issues, liver problems (eg, cirrhosis), breast cancer, or reduced amounts of an enzyme called methemoglobin reductase If you're getting another form of metoclopramide (eg, syrup, orally disintegrating tablet). Some medicines may interact with Reglan. Tell your doctor if you are using any other medicines, particularly any of the following: Monoamine oxidase inhibitors (MAOIs) (eg, phenelzine) since the threat of significant side outcomes (eg, high blood pressure, seizures) could be raised Anticholinergic medication (eg, hyoscyamine) or narcotic soreness medicines (eg, codeine) since they may decrease Reglan's effectiveness Panadol, benzodiazepines (eg, diazepam), cyclosporine, insulin, levodopa, phenothiazines (eg, chlorpromazine), sedatives (eg, zolpidem), discerning serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), succinylcholine, or tetracycline as the chance in their negative effects might be increased by Reglan Cabergoline, digoxin, or pergolide because their usefulness could be decreased by Reglan. This may not really be a whole set of connections that may occur. Ask your doctor if Reglan may interact with additional medications that you just consider. Check with your doctor before you start, stop, or change the dose of any medicine. Crucial security advice: Reglan can cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or particular medications. Use Reglan with warning. Don't drive or perform other potentially unsafe tasks until you understand how you react to it. Tend not to drink alcohol or use medicines that may result in sleepiness (eg, rest assists, muscle relaxers) while you happen to be using Reglan without first checking with your physician; it can enhance their effects. Inquire your pharmacist if you have questions regarding which medicines can trigger drowsiness. Don't simply take more than the suggested serving or use Reglan for longer than 12 months without consulting your doctor. Diabetes sufferers - Reglan may impact your blood glucose. Examine blood sugar levels closely. Request your physician before you change the dosage of your diabetes medicine. Inform your physician or dentist that you simply take Reglan before you receive any health-related or dental hygiene, emergency treatment, or operation. Neuroleptic cancerous syndrome (NMS) is a possibly deadly syndrome which can be caused by Reglan. Symptoms could contain confusion; rigid muscles; fever; strange thinking; swiftly or abnormal heartbeat; and sweating. Contact your physician right away if you have any of these signs. Some sufferers who consider Reglan may possibly develop muscle actions that they cannot get a grip on. This is more likely to happen in elderly sufferers, especially girls. The chance that this may occur or that it will become permanent is greater in those who simply take Reglan in greater dosages or for quite a while. Muscle problems could furthermore occur after short term treatment with reduced doses. Inform your physician right away if you have muscle problems with your arms; legs; or your tongue, face, mouth, or jaw (eg, tongue sticking out, smoking of cheeks, mouth puckering, chewing movements) while taking Reglan. Sufferers who take Reglan might be at higher risk for new or worsening mental or mood changes (eg, depression) or suicidal feelings or actions. Observe patients who take Reglan closely. Contact the doctor at once if new, worsened, or abrupt symptoms like depressed mood or any unusual change in mood or conduct occur. Contact the doctor immediately if any signs of suicidal thoughts or actions occur. Reglan may raise the quantity of a specific hormone (prolactin) in your blood. Symptoms can include enlarged breasts, missed menstrual period, decreased sexual ability, or nipple discharge. Contact your physician immediately in the event that you experience these signs. Lab tests, including liver and kidney function tests, might be carried out while you use Reglan. These tests might be utilized to track your state or check for side effects. Make sure you keep all physician and lab appointments. Use Reglan with caution in the elderly; they may become more sensitive to its effects, especially drowsiness, distress, and uncontrolled muscle movements, including tardive dyskinesia. Reglan must be utilized with extreme caution in children; security and effectiveness in children have not yet been confirmed. The danger of developing uncontrolled muscle movements might be higher in kids. Maternity and breast feeding: In the event that you become pregnant, contact your doctor. You are going to have to talk about the advantages and risks of utilizing Reglan while you're pregnant. Reglan is found in mother's milk. If you are or will be breast feeding while you use Reglan, check with your own physician. Talk about any possible hazards to your baby. A small number of patients have experienced withdrawal symptoms when halting Reglan. These symptoms might include anxiety, dizziness, and headache. 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